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Our results show that there are about 1.1 F1 peptide and 1.2 F2 peptide binding sites on glutathione Sepharose 4B beads, and the disassociation constant of the F2 peptide is lover than that of the F1 peptide (Table 4)

Nowicki, M., Kosacka, J., Serke, H., Blher, M

This is the central limitation of the evidence base, and any honest discussion has to start there

However, the majority of the scientific literature remains preclinical, meaning most studies have been conducted in animal models rather than human clinical trials